Fact & Insights about BPD by John Gunderson

What is BPD is, who is affected, what it does to those who have it, and  

how is it treated   New England Journal of Medicine: 


 Different Brain Regions activated in Impulsive Aggression

A brain imaging study shows that regions responsible for inhibiting aggression are not activated by a serotonergic stimulus in personality-disordered patients with impulsive aggression


Long Journey Led to Advances in Understanding and Treating BPD                              The new findings about BPD upend some early assumptions, such as that the disorder is a life sentence, that is, an expression of "who you are" rather than a disorder you have.    


Glen Gabbard: Gabbard Weds Neurobiology and Psychodynamics in BPD Treatment  


Antonia New: her Studies Uncovered BPD's Neurobiological Secrets  

With a "relentlessly empirical" approach to patients, Antonia New, M.D., has used brain imaging to help establish the neurobiological basis for the troubling behavior associated with borderline personality disorder. 


John Gunderson: BPD Researcher Searches for Puzzle's Missing Piece

 He believes the future of BPD research lies in uncovering the unifying pathway--that accounts for the symptoms that present as borderline personality. 

Stanley BSiever LJ. The interpersonal dimension of borderline personality disorder: toward a neuropeptide model.Am J Psychiatry. 2010 Jan

Attachment and affiliative system may be implicated in the disorder. Neuropeptides, including the opioids, oxytocin, and vasopressin, serve a crucial role in the regulation of affiliative behaviors and thus may be altered in borderline personality disorder. 


Facial emotional expression in reaction to social exclusion in BPD: Staebler, K et al  


The Pain of Exclusion

 Being ignored or lewft out activates areas of the brain associated wiuth physical pain  Scientific America

Sexual Behavior in BPD Randy Sansone, MD
Innovation in Clinical Neurosciance